Inflammatory Biomarkers Predict Domain-Specific Cognitive Decline in Older Adults
نویسندگان
چکیده
منابع مشابه
Predicting cognitive decline in healthy older adults.
OBJECTIVE Authors performed a neuropsychological determination of which individuals in a group of community-dwelling, healthy elderly volunteers would develop cognitive decline. METHODS A group of 155 volunteers reporting good memory and thinking participated in a prospective study over 4 years. Authors monitored cognitive functioning and incidence of Mild Cognitive Impairment (MCI)/Alzheimer...
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BACKGROUND Abnormal cerebrospinal fluid (CSF) biomarker levels predict development of Alzheimer disease with good accuracy and are thought to precede cognitive deterioration. OBJECTIVE To investigate whether changes in CSF biomarker levels over time in healthy older adults are associated with a concurrent decline in cognitive performance. DESIGN Retrospective analysis of longitudinal CSF bi...
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BACKGROUND Increased inflammatory activity and gait speed decline are common with aging, but the association between the two is not well established. The objective of this study was to determine the influence of inflammatory markers, interleukin-6 (IL-6), and tumor necrosis factor alpha, on gait speed performance and decline in older adults. METHODS We conducted cross-sectional and longitudin...
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WHAT WAS THIS STUDY ABOUT? In the article “APOE e4 and the associations of seafood and longchain omega-3 fatty acids with cognitive decline,” van de Rest and colleagues examined the connection between the amount of seafood eaten per week and cognitive decline over approximately 5 years in older adults living in retirement communities. The researchers were also interested in learning more about ...
متن کاملHearing loss and cognitive decline in older adults.
BACKGROUND Whether hearing loss is independently associated with accelerated cognitive decline in older adults is unknown. METHODS We studied 1984 older adults (mean age, 77.4 years) enrolled in the Health ABC Study, a prospective observational study begun in 1997-1998. Our baseline cohort consisted of participants without prevalent cognitive impairment (Modified Mini-Mental State Examination [...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2016
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/glw155